There is no cure for cold sores. Cold sores are caused by the HSV-1 virus, which stays in your body throughout your lifetime. This may sound disheartening—but try not to let it discourage you. Know that your symptoms will come and go, and often, you won’t have any at all. Also know that there are many treatments available to help you manage cold sores.
OTC means "over-the-counter," so you can buy them without a prescription. OTC can include topical medications such as gels, creams or ointments. While OTCs may help some people, others may need a prescription-strength treatment.
Oral vs topical treatments
There are two kinds of prescription treatments for cold sores, oral and topical medicines. Prescription antivirals are taken orally as a pill, while topical medicines, such as gels, creams, or ointments, are applied to the cold sore itself.
Oral and topical medications may have different side effects. Always talk to your doctor about your treatment options. It's important to be an active part of your care to find the treatment that's right for you for managing your cold sores.
What makes XERESE different?
It’s important to remember that XERESE is not a cure—there is no cure for cold sores. But, it can help treat the symptoms, reduce severity, and speed healing time in some patients. See Important Safety Information below.
XERESE® (acyclovir and hydrocortisone) cream 5%/1% is a prescription medicine used in patients ages 6 and older to lessen the healing time of cold sores (herpes labialis) and lessen the chance of a cold sore becoming worse (ulcerating). It should be used early, at the first sign of a cold sore.